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In a very current research, we reported the identification and the characterization of a whole new atypical opioid receptor with exclusive destructive regulatory Homes to opioid peptides.1 Our success confirmed that ACKR3/CXCR7, hitherto referred to as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is likewise a broad-spectrum sca